Having begun their return to the Champions League with a 5-1 demolition at the hands of Eintracht Frankfurt in Germany, Galatasaray have since risen to just outside of the top eight of the table after three successive victories on the continent.
The Turkish giants entertainingly defeated Genclerbirligi in the Super Lig at the weekend to mean that the Turkish champions have now suffered just one defeat in their last 11 matches across all competitions since that defeat to Frankfurt.
After winning the Belgian title for the first time in nearly a century last season, Royale Union Saint-Gilloise began their UEFA Champions League campaign with a surprise but impressive victory over PSV Eindhoven, but things have changed a fair bit since then.
Sebastian Pocognoli departed for Monaco in mid-October and they have lost three on the bounce in Europe since then. They did manage to defeat Cercle Brugge by two goals to nil in Brussels at the weekend, though.
Predicted XI (4-2-3-1): Cakir; Jakobs, Sanchez, Bardakci, Karatas; Sara, Torreira; Sane, Gundogan, Sallai; Yilmaz.
Union SG are likely to make one change to their starting line-up after defender Fedde Leysen was forced off injured against Cercle Brugge last time out.
Predicted XI (3-4-1-2): Scherpen; Mac Allister, Burgess, Sykes; Khalaily, Zorgane, Schoofs, Patris; Rodriguez; Akinpelu, Van de Perre.
