Freiburg have regressed in the Bundesliga this season, which was natural but also potentially a result of them dealing with domestic and Europa League commitments, with just four victories in their 13 matches so far this season.
However, in Europe, they got themselves a much-needed victory in midweek as they recovered from a 2-1 loss to struggling Heidenheim last weekend by edging past ten-man Red Bull Salzburg by a goal to nil, courtesy of a Philipp Lienhart strike.
Borussia Dortmund come into this one on the back of an entertaining 3-2 defeat of Norwegian champions Bodo/Glimt in the league phase of the Champions League, continuing their impressive campaign thus far.
They have suffered just one defeat in their 13 matches in the Bundesliga, having comfortably defeated Hoffenheim by two goals to nil last weekend with goals from Germany internationals Julian Brandt and Nico Schlotterbeck.
Freiburg defender Max Rosenfelder is now sidelined due to a thigh injury for Freiburg, alongside long-term absentee Daniel-Kofi Kyereh, while Eren Dinkci is also a doubt.
Predicted XI (4-2-3-1): Atubolu; Kubler, Ginter, Lienhart, Treu; Eggestein, Osterhage; Beste, Manzambi, Grifo; Holer.
Chelsea loanee Aaron Anselmino has been very impressive this season but picked up an injury in midweek and he is now sidelined alongside Germany international centre-back Waldemar Anton.
Predicted XI (3-4-2-1): Kobel; Can, Sule, Schlotterbeck; Couto, Bellingham, Nmecha, Bensebaini; Beier, Brandt; Guirassy.
